Former U.S. President Donald Trump has ignited controversy by linking the use of acetaminophen (Tylenol) during pregnancy to an increased risk of autism in children. This assertion has been widely rebuked by major medical organizations, which emphasize the lack of conclusive scientific evidence supporting such a claim.
On September 22, 2025, President Trump, alongside Health and Human Services Secretary Robert F. Kennedy Jr., announced new health guidance advising pregnant women to limit the use of acetaminophen, citing potential links to autism and ADHD. They also called for the FDA to notify physicians about these concerns. However, this recommendation contradicts the positions of major medical organizations, including the American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine (SMFM), which continue to endorse acetaminophen as a safe option for pain and fever relief during pregnancy when used appropriately.
The SMFM issued a statement affirming that, based on a thorough review of existing research, no causal relationship has been established between acetaminophen use during pregnancy and an increased risk of autism or ADHD. Similarly, ACOG reiterated that acetaminophen is well-studied and proven to be safe for use in pregnancy, and science does not support claims that its use leads to autism.
The World Health Organization (WHO) also weighed in, stating that current scientific evidence linking paracetamol (acetaminophen) use during pregnancy to autism is inconsistent. WHO emphasized that vaccines are proven to be safe and do not cause autism, urging that scientifically debunked claims should not undermine their value.
In response to the administration’s announcement, the FDA initiated the process for a label change for acetaminophen to reflect evidence suggesting that its use by pregnant women may be associated with an increased risk of neurological conditions such as autism and ADHD in children. The agency also issued a related letter alerting physicians nationwide.
The controversy surrounding President Trump’s comments on acetaminophen and autism underscores the importance of basing public health recommendations on rigorous scientific evidence. While the FDA’s actions may prompt further investigation, the consensus among leading medical organizations remains that acetaminophen is a safe and effective option for pain and fever relief during pregnancy. Pregnant women are advised to consult with their healthcare providers before making any changes to their medication regimen.
